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How to treat chronic pain without a true source

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Posted: Friday, April 11, 2014 9:09 am

Dear Pharmacist: I have chronic pain and take ibuprofen daily plus hydrocodone and celecoxib. I’m willing to do anything right now that could help. The craziest thing is that nothing happened to me, I just developed pain over the years, no accidents, no trauma. Can you help me? — D.W., Boca Raton, Fla.

Pain is a symptom, not a disease itself. It’s a clue that something is out of balance in your system. Without knowing more details it’s hard to hit the nail on the head, so I will give you (and other readers who are suffering in pain) some general information.

Sometimes pain is triggered by foods like gluten or nightshade vegetables, sometimes it is from a nutrient deficiency, and sometimes it is from poor elimination. If you are constipated and toxins back up in your gut or in your blood, then this triggers a physiological response in your body that causes cells to release pain-causing chemicals called “cytokines.”

Two cytokines implicated in pain include the leukotrienes and the prostaglandins. Those are such big names for little substances, but too much of these will make you hurt. Your goal as a pain sufferer is to reduce levels of those.


When you say that out loud, the last syllable sounds like the word “annoyed” and that’s exactly what they do. Leukotrienes spark production of other compounds involved in allergies, food sensitivities, autoimmune disorders and anaphylactic reactions. Leukotrienes tend to increase if you eat food coloring, like yellow dye No. 5, tartrazine, and other artificial substances.

If you have pain, then non-steroidal anti-inflammatory drugs (referred to as “NSAIDs”), such as ibuprofen or naproxen (Advil and Aleve respectively) can help you. The prescription drug Celebrex (celecoxib) can also help.

Since about 2001, the medical literature has shown that dark chocolate can reduce eiconanoids too! Other natural rescue remedies include omega 3 fatty acids, flax seed, perilla seed oil, curcumin and glycyrrhiza. The prescription medications Accolate and Singulair may help too, especially if your problems are primarily allergies.


Excessive amounts of this cytokine occur with arthritis, heavy menstrual cycles, premenstrual syndrome, migraines, multiple sclerosis, chronic lyme disease, as well as colon and breast cancer.

What substances reduce prostaglandins? Fish oils, white willow bark (salix alba), ecklonia cava (a brown algae), meadowsweet (don’t take if you’re allergic to salicylates like aspirin), turmeric, skullcap, ginger root and passionflower. Medications to consider include aspirin, celecoxib, and the NSAID class including ibuprofen and naproxen. Ask your doctor if any of these are right for you.

This information is not intended to diagnose, treat, cure or prevent any disease. For more information about Suzy Cohen, visit her website at



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